Light Fasting Diet and Magnesium in Polycystic Ovary Syndrome (PCOS)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age19-65
SponsorBehnood Abbasi

About this trial

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, which is associated with hormonal imbalances, dyslipidemia, chronic inflammation, and increased oxidative stress, and can increase the risk of cardiovascular and metabolic diseases. Evidence suggests that nutritional interventions play an important role in improving metabolic outcomes in these patients.

This study is a randomized, triple-blind, controlled clinical trial designed to investigate the effect of a light fasting diet combined with magnesium supplementation on lipid profile, lipid peroxidation (malondialdehyde), and C-reactive protein (CRP) levels in women with PCOS. In this study, 46 eligible women were randomly divided into two groups receiving a light fasting diet with magnesium supplementation or placebo, and changes in biochemical and anthropometric indices were evaluated before and after 8 weeks of intervention.

Eligibility criteria

Qualifiers

People between the ages of 19 and 65

People with a body mass index (BMI) ≤ 25

Diagnosis of polycystic ovary syndrome by a specialist based on the Rotterdam criteria

Disqualifiers

Failure of the participant to cooperate during the study

Use of drug therapy that affects carbohydrate or fat metabolism (including oral contraceptives, insulin sensitizers, antiepileptic drugs, antipsychotics, statins, and fish oil) within the past 6 months.

Planning for pregnancy, pregnant, or breastfeeding

In the perimenopausal stage

Trial design

Treatments tested in this trial

  • Light fasting
  • Magnesium supplementation
  • Light fasting
  • Placebo

Treatment groups

46 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Behnood Abbasi

Lead sponsor

Science & Research Islamic Azad University Branch Khozestan

Sponsor institution