Lily's Grace Temporal Interference
ConditionEpilepsy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity of Wisconsin, Madison
About this trial
This study is to evaluate the effectiveness of targeted Transcranial Electrical Stimulation with Temporal Interference (TES-TI) interventions to boost Non-Rapid Eye Movement (NREM) sleep, decrease seizures and promote emotional health in patients with epilepsy. Up to 24 participants (8 control participants for technical optimization prior to recruitment and 16 patients with epilepsy) will be enrolled and can expect to be on study for up to 24 months.
Eligibility criteria
Qualifiers
English-speaking (able to provide consent and complete questionnaires)
Citizen or holding permanent resident status
History of refractory epilepsy with intractable seizures and/or cognitive decline
Disqualifiers
Any current or past history of neurological disorders or acquired neurological disease other than epilepsy (e.g. stroke, traumatic brain injury), including intracranial lesions
Current history of poorly controlled headaches including intractable or poorly controlled migraines
Any systemic illness or unstable medical condition that may cause a medical emergency in case of a provoked seizure (cardiac malformation, cardiac dysrhythmia, asthma, etc.)
Possible pregnancy or plan to become pregnant in the next 6 months
Trial design
Treatments tested in this trial
- TES-TI
- Sham Stimulation
- Structural and Functional MRI
Treatment groups
24 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Wisconsin, Madison
Lead sponsor
Lily's Fund for Epilepsy Research
Collaborator
Source ClinicalTrials.gov