Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-70
SponsorZagazig University

About this trial

Ambulatory surgery places high demands on anesthetic technique. rapid onset and offset of anesthesia, rapid recovery of protective reflexes, mobility and micturition, are required. Since the inception of ambulatory surgery, the favored anesthetic technique has been general anesthesia with short-acting drugs. Concerns about the time to perform spinal anesthesia and the risks of prolonged motor block and urinary retention have limited its use.

Alpha-blockers, lavage fluids for epidural space, insulin, and intravenous lipid emulsions, are still being discussed to shorten and reverse adverse effect of different LAs used for spinal anaesthesia, hence we will evaluate the effectiveness of intravenous lipid emulsion for reversing the neural blockade of spinal anaesthesia in patients undergoing ambulatory surgery.

Eligibility criteria

Qualifiers

Patient acceptance.

Cooperative patient

Age 21-70 years old.

BMI ≤ 35 kg/m2

Disqualifiers

History of allergy to the LA agents used in this study,

Skin lesion at needle insertion site,

Those with bleeding disorders, sepsis, liver disease and psychiatric disorders

History of cognitive dysfunction or mental illness

Trial design

Treatments tested in this trial

  • Intravenous Lipid Emulsion 20%
  • Control (placebo) group

Treatment groups

42 Participants
are divided into 2 treatment groups

Sponsors and collaborators