Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy
ConditionMedian Sternotomy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorTongji Hospital
About this trial
In light of the ongoing controversy surrounding the efficacy of bupivacaine liposomes, our study was designed to investigate, for the first time, the differential postoperative analgesic effects between bupivacaine liposomes combined with bupivacaine hydrochloride and bupivacaine hydrochloride alone in transverse thoracic muscle plane block treatment. The aim is to provide evidence-based medical guidance for drug selection in regional block local anesthesia.
Eligibility criteria
Qualifiers
Patients aged 18-90 years;
ASA Class I ~ III;
Patients undergoing elective median sternotomy.
Disqualifiers
Emergency surgery;
Re-operation;
Coagulation dysfunction;
Preoperative left ventricular function was poor (ejection fraction <35%);
Trial design
Treatments tested in this trial
- Transverse thoracic muscle plane block (TTMPB) using liposomal bupivacaine and bupivacaine mixture
- Transverse thoracic muscle plane block (TTMPB) using bupivacaine hydrochloride
Treatment groups
38 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov