LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhejiang University
About this trial
The goal of this clinical trial is to compare the long-term outcomes of Laparoscopic Ileocecal-Sparing Right Hemicolectomy(LISH) compared to traditional laparoscopic right hemicolectomy(TRH) in the treatment of hepatic flexure colon cancer and proximal transverse colon cancer.
Eligibility criteria
Qualifiers
Age between 18-75 years old
ASA classification ≤III
Colon adenocarcinoma confirmed by endoscopy and pathological biopsy
Enhanced abdominal CT indicating the primary lesion is located in the hepatic flexure of the colon or proximal transverse colon (proximal 1/3 of the transverse colon)
Disqualifiers
Preoperative examination indicates synchronous multiple primary colorectal cancers or other diseases requiring bowel segment resection
Preoperative imaging or intraoperative exploration reveals: 1) tumor involving surrounding organs requiring combined organ resection; 2) presence of distant metastasis; 3) inability to perform R0 resection; 4) fused and fixed lymph nodes at the root of the ileocolic vessels
Additional radical surgery following Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD) procedures
History of any other malignant tumor within the last 5 years or familial adenomatous polyposis, except for cured in situ cervical cancer, basal cell carcinoma, papillary thyroid carcinoma, or skin squamous cell carcinoma
Trial design
Treatments tested in this trial
- LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）
- TRH（Traditional Laparoscopic Right Hemicolectomy）
Treatment groups
568 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov