Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorFondazione IRCCS Istituto Nazionale dei Tumori, Milano
About this trial
This is multicentric, single-arm, observational, investigator-drive study investigating the efficacy of liver transplantation after successful downstaging/disease control of unresectable perihilar cholangiocarcinoma using chemotherapy +/- immunotherapy and stereotactic body radiation therapy (SBRT).
Eligibility criteria
Qualifiers
Transcatheter biopsy or brush cytology
CA-19.9 > 100 mg/ml and/or a mass on cross-sectional imaging with a malignant appearing stricture on cholangiography
Biliary ploidy by FISH with a malignant appearing stricture on cholangiography
Age between 18 years and 70 years
Disqualifiers
Intrahepatic cholangiocarcinoma
Uncontrolled infection
Concomitant malignancies or history of other malignancies in the previous 5 years
Trial design
Treatments tested in this trial
- Not listed
Trial groups
8 Participants
are grouped into 1 trial groupSponsors and collaborators
Source ClinicalTrials.gov