Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases
ConditionBrain Metastases, Adult
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversitaire Ziekenhuizen KU Leuven
About this trial
To observe the quality of life (QOL) and to report on toxicity and outcome parameters after the (repeated) use of local ablative therapy (LAT) i.e. stereotactic radiotherapy (SRT) for patients with multiple (4-10) brain metastases
Eligibility criteria
Qualifiers
Male or female, ≥ 18 years of age
Minimal 4 and up to a maximum of 10 synchronous BM diagnosed on a high resolution contrast-enhanced MRI scan (T1 gadolinium) not dated more than 4 weeks prior to inclusion.
Maximal lesion diameter of single gross tumor volume (GTV) of 3 cm
Maximal cumulative GTV (+CTV for cavity) of 30cm3
Disqualifiers
BM not amenable to SRT
Previous SRT or surgery on the same lesion
Co-morbidities considered clinically precluding the safe use of an MRI examination or SRT
Any psychological, sociological or geographical issue potentially hampering compliance with the study
Trial design
Treatments tested in this trial
- Stereotactic radiotherapy
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov