Locating Biomarkers in OCD Through Behavioral Tasks

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorBaylor College of Medicine

About this trial

Subjects that have a diagnosis of OCD will participate in a clinical interview and cognitive tasks, during which they will be exposed to their individual OC stressors or will be asked to make decisions related to information value and quantity while measuring neural activity and filming facial reactions. This will assist investigators to look for biomarkers of that change. This study offers a unique opportunity to develop biomarkers for key domains of OCD, and other neuropsychiatric disorders, that are grounded in brain neurocircuitry at the individual-patient level.

Subjects will participate in a clinical interview (Day 1), and then tasks+EEG (Day 2). Day 1 will be 4 hours or less, and Day 2 will be 2.5 hours or less.

Eligibility criteria

Qualifiers

Diagnosis of OCD

Non-pregnant if female

Minimum score of 16 on Y-BOCS

Ability to provide informed consent

Disqualifiers

Those not meeting inclusion criteria listed above

Lifetime diagnosis of psychotic disorders such as schizophrenia

Alcohol or substance abuse/dependence within 6 months, excluding nicotine

Deemed at high risk of suicidal behavior or impulsivity

Trial design

Treatments tested in this trial

  • Beads Task
  • PROVOC Tasks

Treatment groups

20 Participants
are divided into 1 treatment group

Sponsors and collaborators

Baylor College of Medicine

Lead sponsor

Brown University

Collaborator

University of Pittsburgh

Collaborator

Butler Hospital

Collaborator