About this trial
The HOMI-LUNG - HAP study is part of the HOMI-LUNG project, funded by the Horizon Europe program. The "HOMI-LUNG" project is an international, interdisciplinary project that aims to better understand the causal links between respiratory tract infections (i.e. pneumonia) and the progression of cardiovascular disease. More specifically, the project aims to quantify the burden of cardiovascular disease after pneumonia and assess patients; acceptability of long-term health alterations, as well as to define pneumonia endotypes with distinct pathobiological mechanisms associated with exacerbation of cardiovascular disease.
Eligibility criteria
Qualifiers
Male or female
Hospitalized for acute coronary syndrome for less than 7 days.
Informed consent from the patient
Person insured under a health insurance scheme
Disqualifiers
Groups A, B, C and D
Age <80 years old
Immunosuppression pre-existing to the index hospitalisation, defined as lymphopenia; 500 elements/mm3, haematologic cancer, aplasia, chemotherapy/radiotherapy for cancer within 3 months prior to the inclusion, or anti-graft rejection drug.
Pregnant women, breastfeeding women.
Trial design
Treatments tested in this trial
- Blood samples
- Oropharyngeal swabs
- ECG
- Cardiopulmonary exercise test, spirometry, plethysmography, pulmonary absorption of carbon monoxide in a single inspiration