Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorJorge Gonzalez-Martinez

About this trial

This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without stimulation. DBS parameters would be adjusted prior to motor testing. Patients would then participate in multiple sessions performing contralateral upper extremity movement tasks measuring movement speed, grip strength, and strength modulation, facial movement, swallowing, and speech tasks.

Eligibility criteria

Qualifiers

Movement disorder patients ≥18 years of age and < 80 years of age, who will be implanted with DBS for treatment of motor symptoms.

Subject has provided written informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorization, where applicable, prior to any study-related procedures.

Disqualifiers

History of seizure disorders

Vasovagal response history and loss of consciousness history

Severe behavioral or cognitive problems that preclude participation in the study, in the opinion of the investigator would impact participation in the study.

Any serious disease or disorder (e.g. cancer, severe cardiac or respiratory disease, neurological conditions other than current movement disorder) or cognitive impairments that could impair ability to participate in this study.

Trial design

Treatments tested in this trial

  • Deep Brain Stimulation (DBS) of the Motor Thalamus

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Jorge Gonzalez-Martinez

Lead sponsor

University of Pittsburgh

Sponsor institution