The study will perform to follow-up UC-MSCs and CM transplantation. 18 patients will be called back to be examined after 5 years of UC-MSC and/or CM transplantation.
Visual field defects at the initial examination with Humphrey perimetry are between 25% to 50%
Willing to sign informed consent as research subjects
Willing to do the peribulbar injection with mesenchymal stem cells isolated from umbilical cord tissue
Willing to do visual field checks with Humphrey's perimetry, vision tests with Snellen boards, Optical Coherent Tomography (OCT) examinations, electroretinogram examinations and fill out a quality of life questionnaire
Pregnant or nursing women
Positive result of HIV test
Have a history of eye tumours
In the immunosuppressive treatment or other drugs that can affect the growth of transplanted stem cells