Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis
ConditionObesity, Morbid
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMayo Clinic
About this trial
It is not known how much improvement in insulin regulated lipolysis (the breakdown of triglycerides) occurs following substantial, sustained weight loss. Researchers will test the effects of inflammation and lipolysis regulation in people before and after bariatric surgery (sleeve gastrectomy) to answer these questions.
Eligibility criteria
Qualifiers
BMI 40 - 50 kg/m2.
Mo active physical illness that would interfere with mobility or weight loss after bariatric surgery
Disqualifiers
Type 1 or Type 2 Diabetes diagnosis or fasting plasma glucose ≥126 mg/dL
Active coronary artery disease
Participation in structured exercise (>2 times per week for 30 minutes or longer)
Smoking
Trial design
Treatments tested in this trial
- Gastric sleeve/bariatric surgery
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov