Longitudinal Oral Microbiome Sampling for BE

ConditionBarrett Esophagus

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorColumbia University

About this trial

This is a longitudinal cohort study to assess the impact of repeated sampling of an oral microbiome signature for Barrett's esophagus (BE). Potential participants will be identified through chart review of patients who have had an endoscopy in the past three years.

Eligibility criteria

Qualifiers

Scheduled for an upper endoscopy or had upper endoscopy within past three years

Eighteen years of age or older

Capable of producing a saliva sample

Able to give informed consent

Disqualifiers

History of head and neck cancer or esophageal squamous cell or gastric cancer

History of esophageal or gastric surgery

Scheduled to undergo colonoscopy on the day of initial saliva collection

Scheduled only for Endoscopic retrograde cholangiopancreatography (ERCP) or Endoscopy ultrasound (EUS) without accompanying standard upper endoscopy on the day of initial saliva collection

Trial design

Treatments tested in this trial

Sample collection

Treatment groups

275 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Columbia University

Lead sponsor

University of Michigan

Collaborator

National Cancer Institute (NCI)

Collaborator

Source ClinicalTrials.gov