About this trial
The investigation will employ a longitudinal approach in which every fetus diagnosed to be SGA (Small for Gestational Age ) will be studied at frequent intervals with sophisticated imaging techniques to assess subtle physiologic changes in the brain, heart, and placenta over time. These findings will be correlated with neurological and cardiovascular function in the newborn and early childhood. This research initiative should yield diagnostic and therapeutic templates that will improve the quality of life of IUGR babies in addition to providing important information that will better inform current diagnostic practices.
Eligibility criteria
Qualifiers
Patients with diagnosed SGA by an ultrasound estimated fetal weight (EFW) of less than the 10th percentile or a fetal abdominal circumference of less than the 5th percentile will be included in the study at the time of their first examination.
Disqualifiers
Patients < 18 years of age, and chromosomal anomalies as identified by regular aneuploidy screening.
Trial design
Treatments tested in this trial
- Ultrasound
- MRI
- Blood collection
- Neurological Function Assessment
- Placental Analysis
- Measurement of body fat
- Pediatric heart ultrasound
Treatment groups
Sponsors and collaborators
University of Colorado, Denver
Lead sponsor
The Perelman Family Foundation
Collaborator