Low Dose Oral Minoxdil in Androgenic Alopecia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorJinnah Postgraduate Medical Centre

About this trial

In order to successfully treat androgenetic alopecia (AGA), this study compares the efficacy of low-dose oral minoxidil dosages of 0.25 mg and 1 mg. It addresses a critical gap in current research, as few studies have examined the relationship between low dosage and outcomes like hair diameter, density, patient satisfaction, and adverse effects, including hypertrichosis. Previous research suggests that low dose of oral minoxidil is a safe and well-tolerated option for hair loss, but the optimal dose for maximizing benefits while minimizing side effects remains unclear. This study aims to determine which dose offers the best balance of efficacy and safety for AGA patients.

Eligibility criteria

Qualifiers

Patients have a clinical and trichoscopic diagnosis of mild to severe AGA

Disqualifiers

Patients who, within three months before the trial, had undergone systemic or topical therapies for AGA

People who suffer from additional hair loss conditions such hyperandrogenism, scarring or inflammatory alopecia, or any hormonal disorders.

Sensitivity to minoxidil

Patients with history of severe systemic diseases (heart, renal, or hepatic), a history of hypertension or hypotension, pregnant and breast-feeding women will also be excluded.

Trial design

Treatments tested in this trial

  • 2.5% Oral minoxidil
  • 1% Oral Minoxidil

Treatment groups

76 Participants
are divided into 2 treatment groups