Low-Dose Total Skin Electron Therapy in Treating Patients With Refractory or Relapsed Stage IB-IIIA Mycosis Fungoides

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorVanderbilt-Ingram Cancer Center

About this trial

This clinical trial studies low- dose total skin electron therapy in treating patients with stage IB-IIIA mycosis fungoides that has not responded to previous treatment (refractory) or has returned after a period of improvement (relapsed). Radiation therapy uses high energy electrons to kill tumor cells and shrink tumors. Rotisserie technique is a method in which the patient receives total skin electron therapy while standing on a rotating platform. Giving low dose total skin electron therapy using rotisserie technique may kill tumor cells, while having fewer side effects, and may allow therapy to be repeated in future if clinically indicated.

Eligibility criteria

Qualifiers

Biopsy confirmed mycosis fungoides stage IB-IIIA

Skin manifestations of mycosis fungoides that are refractory to or have relapsed on at least one prior therapy, which may include topical steroids

Life expectancy > 6 months

Disqualifiers

Serious medical condition that would make treatment unsafe

Pregnant or lactating patient

Trial design

Treatments tested in this trial

  • Quality-of-Life Assessment
  • Objective Grading of Skin Findings

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators

Vanderbilt-Ingram Cancer Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator