Low-intensity Physical-cognitive Exercise and Cognitive Function
ConditionMild Cognitive Impairment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorChiang Mai University
About this trial
This study aims to examine the effects of low-intensity, combined physical-cognitive exercise on cognitive function of older people with mild cognitive impairment (MCI) and identify the mechanisms by which this exercise protocol exerts cognitive function. Older adults with MCI will be recruited to either an exercise or a control group. Low-intensity, combined physical-cognitive exercise will be prescribed to the exercise group 3 times per week for 3 months while the control group will maintain their routine lifestyle. It is hypothesized that at the end of the trial, participants in the exercise group will demonstrate significant improvement in cognitive performance and circulating biomarkers compared to baseline and the control group.
Eligibility criteria
Qualifiers
meeting the criteria for MCI (or mNCD) based on the recent DSM-V criteria
comprehend instructions and able to comply with the study procedures
not taking any medications for their cognition and not planning to start medications during the study trial
Disqualifiers
presence of medical condition(s) unsafe to exercise or affect cognition and mobility
presence of depressive symptoms
exercise regularly
Trial design
Treatments tested in this trial
- combined physical-cognitive exercise
Treatment groups
64 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov