Low Level Light Therapy & Skin Pigmentation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Houston
About this trial
The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease. Participants will have 3 fifteen minute in office LLLT therapy sessions over a period of approximately 7 to 14 days.
Eligibility criteria
Qualifiers
Ability to read and understand the study informed consent in English
Age 18 years or older at enrollment
Individuals with MGD based on one or more of the following clinical signs/symptoms, e.g., meibum quality score of 1-3 (Bron et al.), meibography score of 1, 2, or 3 on the Pult Meiboscale, non-invasive 1st tear break up time of 10 seconds or less, or an Ocular Surface Disease Index (OSDI) score greater than 12 points.
Disqualifiers
Active anterior segment pathology (e.g., bacterial conjunctivitis, microbial keratitis)
History of systemic disease associated with aqueous-deficient dry eye disease (e.g., Sjogren's syndrome)
History of corneal surgery, refractive surgery, or eyelid surgery within 6 months
History of corneal ectasia (e.g. keratoconus, Pellucid marginal degeneration)
Trial design
Treatments tested in this trial
- Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov