About this trial
Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.
Recently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.
The aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.
Eligibility criteria
Qualifiers
ASA I - II.
Adult patients scheduled for laparoscopic nephrectomy.
Disqualifiers
Patient refusal.
Contraindication to regional anesthesia (e.g., coagulopathy, site infection).
Allergy to local anesthetics.
Trial design
Treatments tested in this trial
- Low-Thoracic Epidural Anesthesia
- General Anesthesia
Treatment groups
Sponsors and collaborators
Nazmy Edward Seif
Lead sponsor
Cairo University
Sponsor institution