About this trial
This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or diagnosed with COPD. Annual LDCT, spirometry, and serum biomarker tests will be conducted over 3 years, and a follow-up lasting up to 10 years.
Eligibility criteria
Qualifiers
Current smokers (>20 pack-years)
Former smokers (>20 pack-years) who have quit within the past 15 years,
Non-smokers exposed to wood smoke more than 100 hours/year
Patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD).
Disqualifiers
Subjects who cannot be examined by tomography due to physical limitations such as weight.
History of any type of cancer within the last five years, except non-melanoma skin cancer.
Symptoms consistent with some malignant neoplasm.
People with a poor physical-emotional condition that reduces their life expectancy or does not ensure adherence to the study.
Trial design
Treatments tested in this trial
- Screening