Lung Cancer Screening With Low-dose CT Scan in Women : Implementation Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age50-74
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

The purpose of this study is to determine whether reading of low-dose thoracic CT scans can be done by a single general radiologist who has been trained to lung cancer screening, and will evaluate the performance in comparison with double reading by experts.

The study will enroll women between 50 and 74 years old, at risk for lung cancer due to their smoking history.

Eligibility criteria

Qualifiers

Women aged from 50 to 74 years

who had smoked at least 20 pack years and quit less than 15 years ago

Had given their consent and accepted the need for a 2-year follow-up

Affiliated to the social security system

Disqualifiers

Presence of clinical symptoms suggesting malignancy (weight loss, hemoptysis) or ongoing infection (cough with fever)

Evolving cancer

History of lung cancer

A 2-year follow-up not possible

Trial design

Treatments tested in this trial

  • Low-dose computed tomography of the chest

Treatment groups

2,635 Participants
are divided into 1 treatment group

Sponsors and collaborators

Assistance Publique - Hôpitaux de Paris

Lead sponsor

Ministère de la Santé et des Solidarités

Collaborator

National Cancer Institute, France

Collaborator

URC-CIC Paris Descartes Necker Cochin

Collaborator