Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Florida

About this trial

The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.

Eligibility criteria

Qualifiers

Signed informed consent

Male or female 18 years of age or older

Negative pregnancy test for women of childbearing potential

Hemoglobin >12.5 g/dl measured on the day of participation

Disqualifiers

Pregnancy or breastfeeding

Weight < 50 kg

History of anemia requiring blood transfusions, erythropoietin supplementation, or iron supplementation within the past 36 months

Known hemoglobin <12.5 g/dl within the past 90 days

Trial design

Treatments tested in this trial

  • History and physical exam.
  • Blood draw.
  • Pulmonary function testing.
  • Albuterol inhaler.

Treatment groups

220 Participants
are divided into 3 treatment groups

Sponsors and collaborators