LVAD Conditioning for Cardiac Recovery
ConditionHeart Failure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSTAVROS G DRAKOS
About this trial
The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the heart. Multiple previous studies have shown that interventions like this may improve heart function and give patients the opportunity for a better quality of life.
Eligibility criteria
Qualifiers
Diagnosed with heart failure undergoing LVAD implantation as a bridge to transplant
Enrolled in the Effects of Mechanical Unloading on Myocardial Function and Structure study (IRB 30622)
Disqualifiers
Neither the subject nor the subject's representative is willing to provide written consent for participation
Subjects with adverse events leading to hospitalization during the optimum unloading phase are excluded from participation in the controlled reloading phase
Trial design
Treatments tested in this trial
- Controlled Cardiac Reloading through LVAD Speed Adjustment
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
STAVROS G DRAKOS
Lead sponsor
University of Utah
Sponsor institution
Source ClinicalTrials.gov