Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
ConditionGlioma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorShengjing Hospital
About this trial
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.
Eligibility criteria
Qualifiers
age older than 18 years
Karnofsky performance status higher than 60
with written informed consent
MRE performed within one week before surgery
Disqualifiers
previous treatment for glioma
inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia)
completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude)
failure to proceed with surgery after MRE
Trial design
Treatments tested in this trial
- Magnetic Resonance Elastography
- Assessment and Recording
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov