Magnetic Resonance Imaging in Patients with Trigeminal Neuralgia
ConditionTrigeminal Neuralgia (TN)
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorTongji Hospital
About this trial
This study intends to use MRI technology to analyze the dynamic changes and microstructure changes of the brain network in patients with trigeminal neuralgia, evaluate the blood-brain barrier and water exchange rate, and further analyze their correlation with clinical indicators, so as to explore the changes in brain structural plasticity and potential neural mechanisms
Eligibility criteria
Qualifiers
The diagnosis was TN according to the ICHD.
Patients requiring surgical treatment due to ineffective or intolerant treatment with carbamazepine or oxasepine before operation;
First surgical treatment;
Right-handed dominant;
Disqualifiers
Secondary TN;
Associated with other types of chronic pain or neuropsychiatric disorders;
History of head trauma or stroke or cerebrovascular ischemia;
History of microvascular decompression or other treatments (gamma knife radiosurgery, etc.);
Trial design
Treatments tested in this trial
- Not listed
Trial groups
120 Participants
are grouped into 2 trial groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov