Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
ConditionHeart Failure, Congestive
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorJohns Hopkins University
About this trial
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
Eligibility criteria
Qualifiers
age > 18 years
Healthy subjects: no history of heart disease
Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) <40%
Left ventricular hypertrophy: wall thickness >1.2cm
Disqualifiers
contraindication to MRI
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov