About this trial
The purpose of this research is to learn more about how the brain works in people with essential tremor, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). Essential tremor is a movement disorder that causes shaking, usually in the hands, and can make everyday tasks difficult. HiFU is a treatment that uses focused sound waves to target a small area in the brain involved in tremor. In this study, the investigators aim to understand how this treatment affects the brain's networks by using safe, non-invasive tests such as brain imaging, brain wave recordings, and movement assessments.
Eligibility criteria
Qualifiers
Age >50 years and <85 years
Refractory to at least 2 first line tremor medications
Skull Density Ratio (SDR) > = 0.35
MR/MEG incompatible implants and implantable devices (ex: pacemaker)
Disqualifiers
None
Trial design
Treatments tested in this trial
- MRI and fMRI scans
- MEG
- Sensor-based motor assessments
- Clinical evaluations
- Questionnaires and rating scales that