Magnetoencephalography (MEG) Pilot Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-84
SponsorUniversity of Florida

About this trial

The purpose of this research is to learn more about how the brain works in people with essential tremor, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). Essential tremor is a movement disorder that causes shaking, usually in the hands, and can make everyday tasks difficult. HiFU is a treatment that uses focused sound waves to target a small area in the brain involved in tremor. In this study, the investigators aim to understand how this treatment affects the brain's networks by using safe, non-invasive tests such as brain imaging, brain wave recordings, and movement assessments.

Eligibility criteria

Qualifiers

Age >50 years and <85 years

Refractory to at least 2 first line tremor medications

Skull Density Ratio (SDR) > = 0.35

MR/MEG incompatible implants and implantable devices (ex: pacemaker)

Disqualifiers

None

Trial design

Treatments tested in this trial

  • MRI and fMRI scans
  • MEG
  • Sensor-based motor assessments
  • Clinical evaluations
  • Questionnaires and rating scales that

Treatment groups

10 Participants
are divided into 1 treatment group

Sponsors and collaborators