Management of Patients With New Left Bundle Branch Block After Transcatheter Aortic Valve Implantation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique Hopitaux De Marseille

About this trial

The purpose of this study is to show that Electrocardiogram Ambulatory Monitoring-guided strategy is superior to ElectroPhysiological Study on the rate of alive patients with an appropriate Pacemaker implantation/non-implantation, at 12 months after randomization, in patients with New Onset Persistent Left Bundle Branch Block after Transcatheter Aortic Valve Implantation.

Eligibility criteria

Qualifiers

Presenting with New Onset Persistent Left Bundle Branch Block, defined as a new Left Bundle Branch Block >150 ms that persists at least two days after Transcatheter Aortic Valve Implantation and is stable

With an anticipated life expectancy >1 year

Who consent to participate to the study

Disqualifiers

Documented high grade Atrio Ventricular block (Atrio Ventricular block of a degree higher than Mobitz I)

Persistent PR interval prolongation > 240 ms

Occurrence of syncope or sudden cardiac death,

Identification of any indisputable criteria for Pacemaker implantation

Trial design

Treatments tested in this trial

  • Transcatheter Aortic Valve Implantation

Treatment groups

360 Participants
are divided into 2 treatment groups