Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)

ConditionsRespiratory Failure Without Hypercapnia Respiratory Failure With Hypercapnia Postoperative Respiratory Complication

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorAssiut University

About this trial

Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.

Eligibility criteria

Qualifiers

Age above 18 years

within 48 hours after major surgery

PAO2/FIO2 less than 200

Signs of respiratory distress and respiratory rate (RR) more than 25 cycles/minute

Disqualifiers

Age below 18 years

Pregnant ladies

Orofacial trauma or burns

Active Gastrointestinal bleeding

Trial design

Treatments tested in this trial

BIPAP
Vapotherm

Treatment groups

180 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Assiut University

Lead sponsor

Source ClinicalTrials.gov