Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Intercommunal Creteil

About this trial

To evaluate the regenerative capacities of mesenchymal cells composing the microenvironment of alveolar type 2 cells in a population of patients, undergoing thoracic surgery for suspected cancer, who are smokers with and without COPD compared to non-smokers patients

Eligibility criteria

Qualifiers

Age ≥ 18

Patient undergoing lung resection surgery (lobectomy, pneumonectomy, segmentectomy) for cancer or suspected cancer

Acceptance to participate in the protocol

Affiliated to a social security plan

Disqualifiers

Chronic autoimmune disease

Patient under guardianship or curators

Neo-adjuvant chemotherapy

History of thoracic radiotherapy

Trial design

Treatments tested in this trial

  • Thoracic resection surgery

Treatment groups

186 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Hospitalier Intercommunal Creteil

Lead sponsor

Henri Mondor University Hospital

Collaborator

Institut National de la Santé Et de la Recherche Médicale, France

Collaborator