Massed Prolonged Exposure for PTSD in Substance Use Treatment

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVeterans Medical Research Foundation

About this trial

The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are:

* Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.

Eligibility criteria

Qualifiers

Veterans

age 18+

who have served since September 2001

who are enrolled in a SUD IOP at a participating VA

Disqualifiers

severe cognitive impairment

current suicidal or homicidal intent requiring immediate treatment

current unstable psychotic or manic symptoms not attributable to SUD

Trial design

Treatments tested in this trial

  • Prolonged Exposure Therapy

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Veterans Medical Research Foundation

Lead sponsor

University of Minnesota

Collaborator

Center for Veterans Research and Education

Collaborator