Maternal Characteristics Associated With Child Growth and Adiposity

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorInstituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri

About this trial

The goal of this observational study is to investigate the concentrations of leptin, insulin, liver expressed antimicrobial peptide 2 (LEAP2), and cortisol in plasma and breast milk and their relationship with eating behavior, growth, adiposity and with the levels of these hormones in infants, comparing mothers with normal weight and with pre-pregnancy overweight/obesity. The main question\[s\] it aims to answer are:

* Are maternal hormones associated with child growth and adiposity * Are maternal hormone receptors associated with child growth and adiposity * Are infant hormones and their receptors associated with child growth and adiposity * Are maternal and infant hormones and their receptors associated with child eating behavior Participants will provide milk and blood samples. Researchers will compare mothers with normal weight and with pre-pregnancy overweight/obesity to see if there are differences in child growth and adiposity .

Eligibility criteria

Qualifiers

Lactating women with pre-pregnancy normal weight and overweight or obesity as described by the World Health Organization.

Disqualifiers

Diabetes (Type I or II or gestational)

Multiple pregnancy

Hypertensive disorders during pregnancy

Delivery of pre-term infant (<37 weeks).

Trial design

Treatments tested in this trial

  • overweight/obesity

Treatment groups

130 Participants
are divided into 2 treatment groups