About this trial
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.
Eligibility criteria
Qualifiers
Maternal Grandmother' grandchildren delivered in Guangzhou Women and Children's Medical Center
Baseline information of maternal grandmother's daughter during pregnancy available
Disqualifiers
Significant cardiovascular abnormalities
Intelligent obstacle, intellectual disabilities or gawkish condition
Trial design
Treatments tested in this trial
Treatment groups
Sponsors and collaborators
Guangzhou Women and Children's Medical Center
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Collaborator
University of Birmingham
Collaborator