About this trial
In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases. This approach also seeks to reduce the frequency with which children require general anesthesia for treatment.
Eligibility criteria
Qualifiers
Diagnosis of Port Wine Stain.
Age Range: 2mo to 18 years of age.
Stable PWS: The port wine stain should be stable, meaning there is no active inflammation or infection present, and it should not be changing in size or color due to factors like injury or disease.
signed Consent: For ethical reasons, participants must be able to provide informed consent. In the case of minors, consent would generally be required from a parent or legal guardian.
Disqualifiers
severe allergies to anesthesia
active skin infections or inflammation
recent laser therapy
use of Photosensitizing medications
Trial design
Treatments tested in this trial
- Pulse Dye laser
- Pulse Dye Laser (PDL) pulse width stacking
- Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.
- IPL (Intense Pulsed Light) followed by Pulse Dye Laser (PDL)
- Cupping followed by Pulse Dye Laser (PDL)