MCE Identifying Bleeding Lesions in Patients with Antiplatelet Drugs-Related Acute Non-Hematochezia Gastrointestinal Bleeding

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChanghai Hospital

About this trial

The goal of this clinical trial is to explore the diagnostic efficacy of detachable string magnetically controlled capsule endoscopy (ds-MCE) for identification of bleeding lesions in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding. The main questions it aims to answer are:

Compared to the conventional esophagogastroduodenoscopy, does ds-MCE accurately detect bleeding lesions in the upper gastrointestinal tract in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding? Recording bleeding lesions in the small bowel detected by ds-MCE in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding.

Participants will:

Undergo ds-MCE first and subsequently EGD within 24 hours. Receive follow-up in the following 30days.

Eligibility criteria

Qualifiers

No gender limit, age ≥ 18 years;

Acute non-hematochezia gastrointestinal bleeding symptoms, including haematemesis or melena;

Taking antiplatelet drugs continuously for at least 14 days;

Hemodynamically stable;

Disqualifiers

Age < 18 years;

Hemodynamically unstable even after initial volume resuscitation and/or have ongoing fresh hematemesis at presentation;

With upper gastrointestinal bleeding caused by peptic ulcer or acute gastric mucosal lesion within 1 month before inclusion;

History of endoscopic therapy (such as ESD, EMR, etc.) within 1 month before inclusion;

Trial design

Treatments tested in this trial

  • ds-MCE and EGD examinations

Treatment groups

204 Participants
are divided into 1 treatment group

Sponsors and collaborators

Changhai Hospital

Lead sponsor

First Affiliated Hospital Xi'an Jiaotong University

Collaborator

Qilu Hospital of Shandong University

Collaborator