About this trial
The goal of this clinical trial is to explore the diagnostic efficacy of detachable string magnetically controlled capsule endoscopy (ds-MCE) for identification of bleeding lesions in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding. The main questions it aims to answer are:
Compared to the conventional esophagogastroduodenoscopy, does ds-MCE accurately detect bleeding lesions in the upper gastrointestinal tract in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding? Recording bleeding lesions in the small bowel detected by ds-MCE in patients with antiplatelet drugs-related acute non-hematochezia gastrointestinal bleeding.
Participants will:
Undergo ds-MCE first and subsequently EGD within 24 hours. Receive follow-up in the following 30days.
Eligibility criteria
Qualifiers
No gender limit, age ≥ 18 years;
Acute non-hematochezia gastrointestinal bleeding symptoms, including haematemesis or melena;
Taking antiplatelet drugs continuously for at least 14 days;
Hemodynamically stable;
Disqualifiers
Age < 18 years;
Hemodynamically unstable even after initial volume resuscitation and/or have ongoing fresh hematemesis at presentation;
With upper gastrointestinal bleeding caused by peptic ulcer or acute gastric mucosal lesion within 1 month before inclusion;
History of endoscopic therapy (such as ESD, EMR, etc.) within 1 month before inclusion;
Trial design
Treatments tested in this trial
- ds-MCE and EGD examinations
Treatment groups
Sponsors and collaborators
Changhai Hospital
Lead sponsor
First Affiliated Hospital Xi'an Jiaotong University
Collaborator
Qilu Hospital of Shandong University
Collaborator