Measurement Of NT-proBNP to Predict Outcomes in Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNorfolk and Norwich University Hospitals NHS Foundation Trust

About this trial

The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determine which patients are at risk of an adverse outcome, such as a heart attack or death.

Eligibility criteria

Qualifiers

Patients who are equal to or over 18 years old

Infrainguinal arterial reconstruction

Aortic aneurysm

Aorto-bifemoral bypass / or aortic endarterectomy

Disqualifiers

Patients undergoing emergency surgery

Those who are unable or unwilling to give informed consent

Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris)

Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

200 Participants
are grouped into 2 trial groups