Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorTomsk National Research Medical Center of the Russian Academy of Sciences
About this trial
The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary microvascular dysfunction in chronic coronary heart diseasу.
Eligibility criteria
Qualifiers
Ischemia with no obstructive coronary arteries (INOCA)
Obstructive coronary artery disease (CAD)
Patients without evidence of coronary heart disease
Disqualifiers
Left ventricular ejection fraction <55% according to echocardiography;
History of myocardial infarction/revascularization;
hypertension: systolic blood pressure >180 mm Hg. Art., diastolic BP>110 mm Hg. Art.;
systolic arterial hypotension <80 mm Hg. Art.;
Trial design
Treatments tested in this trial
- dynamic SPECT (two-day rest/stress protocol)
- gated myocardial perfusion imaging
- blood sampling
- Low Dose CT-scan
- CT-coronary angiography
Treatment groups
75 Participants
are divided into 3 treatment groupsSponsors and collaborators
Tomsk National Research Medical Center of the Russian Academy of Sciences
Lead sponsor
Russian Science Foundation
Collaborator
Source ClinicalTrials.gov