Mechanical Power and Driving Pressure Exposure in Laparoscopic Surgery

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIstinye University

About this trial

Postoperative pulmonary complications (PPCs) remain an important cause of morbidity after abdominal surgery. Intraoperative mechanical ventilation may contribute to lung injury through the mechanical load applied to the respiratory system. Mechanical power (MP) and driving pressure (DP) have emerged as integrative parameters reflecting the total ventilatory burden delivered to the lungs.

This prospective observational study aims to evaluate the association between time-dependent exposure to intraoperative mechanical power and driving pressure and postoperative pulmonary outcomes in patients undergoing elective laparoscopic abdominal surgery. Ventilatory parameters will be recorded at predefined intervals during routine clinical care, and MP and DP will be calculated without altering clinical management. The primary objective is to assess whether longer exposure to elevated ventilatory load is associated with the development of postoperative pulmonary complications.

Eligibility criteria

Qualifiers

Age ≥ 18 years

Scheduled for elective laparoscopic abdominal surgery under general anesthesia

Intraoperative mechanical ventilation with volume-controlled ventilation

Provision of written informed consent

Disqualifiers

Emergency surgery

Conversion to open surgery

Preoperative invasive or noninvasive mechanical ventilation

Intraoperative major complications requiring substantial deviation from routine ventilation management

Trial design

Treatments tested in this trial

  • Intraoperative Ventilatory Load Exposure (Mechanical Power and Driving Pressure)

Treatment groups

No treatment groups listed

Sponsors and collaborators