Mechanical Power During Different Ventilation Modes in Laparoscopic Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

About this trial

This study investigates how different breathing machine (ventilator) settings affect the energy delivered to the lungs during surgery. Mechanical power is a measure of this energy, and high levels can sometimes lead to lung irritation. In clinical practice, a mode called Pressure-Regulated Volume Control (PRVC) is often used because it lowers the "peak" pressure in the airways, which is generally thought to be safer. However, doctors have noticed that even though the peak pressure goes down in PRVC mode, the total mechanical power displayed on the monitor might actually increase compared to the standard Volume-Controlled Ventilation (VCV) mode. In this study, patients undergoing gallbladder surgery will be monitored using both ventilation modes in a random order. The researchers will compare the machine-calculated mechanical power for both modes to see if the perceived benefit of lower peak pressure in PRVC actually results in lower overall energy transfer to the lungs.

Eligibility criteria

Qualifiers

Patients undergoing elective laparoscopic cholecystectomy surgery.

Patients between 18 and 75 years of age.

American Society of Anesthesiologists (ASA) physical status I, II or III.

Body Mass Index (BMI) between 18.5 and 35 kg/m².

Disqualifiers

History of significant chronic obstructive pulmonary disease (COPD) or asthma.

Previous lung resection or major thoracic surgery.

Heavy smokers (more than 20 cigarettes per day).

Presence of spontaneous breathing effort during mechanical ventilation.

Trial design

Treatments tested in this trial

  • Volume-Controlled Ventilation (VCV)
  • Pressure-Regulated Volume Control (PRVC)

Treatment groups

80 Participants
are divided into 2 treatment groups

Locations

This trial has no locations