Mechanisms for Laser-Induced Rejuvenation
ConditionSkin Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWright State University
About this trial
It has shown that laser wounding of geriatric skin protects it against skin cancer. The purpose of this study is to determine the origin of cells called fibroblasts which are present after treatment with Fractionated Laser Resurfacing (FLR). These cells restore a youth-like ultraviolet B (UVB) response, but where they come from is currently unknown. The study recruits subjects who are scheduled to undergo abdominoplasties to investigate the origin of those cells stimulated by laser treatment.
Eligibility criteria
Qualifiers
Adult males and females 18 and older
Able to comprehend procedures and risks
Planning to undergo abdominoplasty surgery
Minimum amount of skin to be removed is 50 x 20cm
Disqualifiers
Medical history of not well-controlled diabetes. This is defined as a subject who needs high doses of insulin, recent history of hospitalization for diabetes-related complications, or poor wound health as evidenced by diabetic ulcers. Subjects who have been deemed healthy enough for abdominoplasty surgery would tend to suggest that their diabetes should not be an issue. However, if the subjects have diabetic complications as outlined above, they could affect the wound healing which is the object of this protocol so they would be excluded.
Pregnant or nursing
History of pathologically abnormal wound healing such as keloidal scars
Existing tattoos on the abdomen that are so extensive that they could interfere with the study
Trial design
Treatments tested in this trial
- Fractionated Laser Resurfacing
Treatment groups
12 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov