About this trial
The goal of this clinical trial is to learn if dTMS targeting the ACC can be used to rapidly and effectively treat AN. A randomized controlled study design is adopted, in which patients with AN are divided into the CBT+dTMS treatment group and CBT+pseudostimulation group by 1:1 randomization, followed by a 6-week intervention and a half-year follow-up to clarify whether CBT combined with dTMS is superior to single CBT treatment for AN.
Eligibility criteria
Qualifiers
Female, aged 18-35 years, right handedness.
Above primary education.
Meet the diagnostic criteria of AN in DSM-V, and13.0 kg/m2 ≤ body mass index (BMI)<18.5 kg/m2.
No systemic nutritional therapy, psychiatric medication or any form of psychotherapy have been received within 1 month before enrollment.
Disqualifiers
Diagnosed with a DSM-5 disease other than anorexia nervosa, or at high risk of suicide, strong impulsive behavior as well as anti-social behavior.
With severe physical or cognitive impairment.
Not able to undergo MRI.
Considered unsuitable for enrollment in this clinical trial for other reasons.
Trial design
Treatments tested in this trial
- Deep transcranial magnetic stimulation
- cognitive behavior therapy
- Sham deep transcranial magnetic stimulation
- Basic treatment