Mechanisms Of Disease Progression in Aortic Stenosis - the MODAS Study
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHeinrich-Heine University, Duesseldorf
About this trial
Biomarkers and mechanisms in the progression of aortic valve stenosis are sometimes not sufficiently understood. The current project will take into account image morphological and immunological aspects that predict the development of hemodynamically relevant aortic valve stenosis in order to identify high-risk patients and to develop further therapeutic options.
Eligibility criteria
Qualifiers
The patient has an acquired (tricuspid) moderate aortic valve stenosis, which is the reason for regular outpatient cardiological care.
The subject has been informed verbally and in writing about the study and has given written consent to participate in this study.
Age > 18 years
Disqualifiers
The subject has contraindications for the performance of a magnetic resonance imaging or computed tomography (e.g., severe arrhythmias , contrast agent intolerance, a pacemaker, or severe renal insufficiency or severe renal insufficiency or claustrophobia).
Presence of only mild or already high-grade acquired tricuspid Aortic valve stenosis
Patient with bicuspid aortic valve
Inability to follow the instructions of study personnel
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Heinrich-Heine University, Duesseldorf
Lead sponsor
German Research Foundation
Collaborator
University of Bonn
Collaborator
University Cologne
Collaborator
Collaborative Research Center
Collaborator
Source ClinicalTrials.gov