Mechanisms of Resistance Exercise Training for Improved Muscle Insulin Sensitivity

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-50
SponsorMayo Clinic

About this trial

To uncover the underlying mechanisms of resistance exercise training benefits on glucose metabolism and insulin sensitivity in muscle.

Eligibility criteria

Qualifiers

Sedentary (≤30min of physical activity on ≤1 day/week)

Weight stable for ≥3 months prior to study

Disqualifiers

Active coronary artery disease or heart failure.

Participation in a structured exercise program > 1 day/week.

Abnormal liver function test results (Transaminase >2 times the upper limit of normal)

Abnormal renal function test results (calculated GFR <60 mL/min/1.73m2); If on antihypertensive, thyroid, anti-depressant or lipid lowering medication, lack of stability on the medication for the past 2 months prior to enrollment in the study

Trial design

Treatments tested in this trial

  • Resistance Exercise Training

Treatment groups

16 Participants
are divided into 1 treatment group

Sponsors and collaborators

Mayo Clinic

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator