About this trial
To uncover the underlying mechanisms of resistance exercise training benefits on glucose metabolism and insulin sensitivity in muscle.
Eligibility criteria
Qualifiers
Sedentary (≤30min of physical activity on ≤1 day/week)
Weight stable for ≥3 months prior to study
Disqualifiers
Active coronary artery disease or heart failure.
Participation in a structured exercise program > 1 day/week.
Abnormal liver function test results (Transaminase >2 times the upper limit of normal)
Abnormal renal function test results (calculated GFR <60 mL/min/1.73m2); If on antihypertensive, thyroid, anti-depressant or lipid lowering medication, lack of stability on the medication for the past 2 months prior to enrollment in the study
Trial design
Treatments tested in this trial
- Resistance Exercise Training
Treatment groups
Sponsors and collaborators
Mayo Clinic
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator