Mechanisms Underlying Hypoxic, Heat and Cross-tolerance Adaptation in Women
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorJozef Stefan Institute
About this trial
This study will consist of a parallel-groups design, with 30 healthy active female participants randomly assigned to either an experimental heat acclimation and exercise intervention, or a thermo-neutral exercise intervention control group. Interventions will be 10 days in duration, and consist of daily 60-minute exercise bouts under the appropriate environmental condition. Before and after each intervention, various tests will be conducted to establish exercise capacity under various environmental conditions, as well as underlying mechanisms of physiological adaptation induced by each intervention.
Eligibility criteria
Qualifiers
Age: 18 - 35 years
Body mass index: 18.5 - 25.0 kg/m²
Regular physical activity (at least 30 minutes of moderate-intensity activity, three times per week)
Disqualifiers
Habitual smoker within the past 5 years
History of metabolic disorders or any medications deemed to pose an undue risk or introduce bias in any outcome measures
Exposure to altitude > 2000 m above sea level within four weeks of scheduled participation
Permanent residence at altitude > 1000 m above sea level
Trial design
Treatments tested in this trial
- Heat acclimation and exercise training
- Thermo-neutral exercise training group
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Jozef Stefan Institute
Lead sponsor
University of Ljubljana
Collaborator
University of Ljubljana, Faculty of Medicine
Collaborator
Source ClinicalTrials.gov