Mechanistic Interventions and Neuroscience of Dissociation

ConditionDissociation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorEmory University

About this trial

The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people. The intervention will be tested in dissociative traumatized people at two sites: Emory University and University of Pittsburgh. The researchers are interested in whether neural networks associated with attentional control and interoceptive awareness can be enhanced in this population. The researchers propose to evaluate whether different body-focused and non-body focused interventions can change these mechanisms.

Eligibility criteria

Qualifiers

experience of at least one Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Criterion A trauma (assessed using the Life Events Checklist)

a score of 7 or higher on the Multiscale Dissociation Inventory (MDI) depersonalization subscale

willingness to participate in the study

Disqualifiers

actively psychotic and cognitively compromised individuals (assessed using the Moderate-severe cognitive impairment screening tool (MoCA) will be excluded

moderate or more severe substance dependence (assessed with the MINI)

persons with imminent risk of physical violence to self or others

Trial design

Treatments tested in this trial

  • Vibration
  • Breath Focus
  • No Distractions

Treatment groups

350 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Emory University

Lead sponsor

National Center for Complementary and Integrative Health (NCCIH)

Collaborator