Mediators of Loin Pain in IgA Nephropathy
ConditionIgA Nephropathy (IgAN)
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Leicester
About this trial
The goal of this observational study is to learn about loin pain in people with Immunoglobulin A nephropathy (IgAN).
The main question it aims to answer is:
What changes occur in the kidneys, urine, and blood when people with IgAN experience loin pain?
Participants will have MRI scans of their kidneys, provide urine and blood samples, and have their latest kidney function test results reviewed. For participants who experience loin pain, these assessments will be carried out during a pain episode and again when they are pain-free, so the results can be compared.
Eligibility criteria
Qualifiers
≥18 years of age at the time of recruitment
IgAN diagnosis confirmed with a renal biopsy
Episodic/Intermittent Loin Pain (defined as pain at least once every 6 months)
Have the capacity to consent to the study Cohort B
Disqualifiers
Constant loin pain
Infrequent loin pain (no pain experienced in the last 6 months)
Inability to differentiate loin pain from back pain
Other renal diseases
Trial design
Treatments tested in this trial
- Not listed
Trial groups
40 Participants
are grouped into 2 trial groupsSponsors and collaborators
University of Leicester
Lead sponsor
University Hospitals, Leicester
Collaborator
Source ClinicalTrials.gov