Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs

ConditionsOsteonecrosis of the Jaw Osteonecrosis Due to Drugs, Jaw Osteonecrosis Due to Drug Bisphosphonate-Associated Osteonecrosis Bisphosphonate-Associated Osteonecrosis of the Jaw

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorCatholic University of the Sacred Heart

About this trial

The objective of this prospective observational study is to investigate the incidence of Medication Related Osteonecrosis of the Jaws (MRONJ) in patients receiving antiresorptive drugs for oncohematologic reasons during a 5-year follow-up. Secondary objectives are to compare the different antiresorptive drugs in relation to the incidence of MRONJ and to identify any systemic as well as local risk factors.

Eligibility criteria

Qualifiers

Patients with specific prescription to initiate therapy with antiresorptive drugs

Disqualifiers

Previous Head and Neck Radiotherapy

Trial design

Treatments tested in this trial

Dental management

Treatment groups

126 Participants

are divided into 1 treatment group

Sponsors and collaborators

Catholic University of the Sacred Heart

Lead sponsor

Source ClinicalTrials.gov