Medico-economic Evaluation of Anti-VEGF Treatments in the Treatment of naïve Age-related Macular Degeneration (AMD): a Model Adapted to the French Context

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

Age-related macular degeneration (AMD) is the leading cause of blindness after 50 years in industrialized countries, compromising daily activities and reducing quality of life. And whose treatment is one of the first health expenditures. Since September 2015, Bevacizumab, which does not have marketing authorization in AMD, has been given a temporary recommendation for use. Studies in other countries have shown that bevacizumab is cost-effective in the treatment of AMD compared to other anti-VEGF therapies used.

Eligibility criteria

Qualifiers

Naive neovascular AMD form of retro localization foveal, unilateral or bilateral (one eye per patient will be studied),

Patients to be treated with intravitreous injections of Bevacizumab or Ranibizumab or Aflibercept,

Patient using effective contraception if he is of childbearing age

Patient informed and not having made his opposition to the research,

Disqualifiers

Previous or current treatment of AMD by intravenous injection of anti-VEGF or surgery dating less than 2 months in the studied eye,

Contraindications to the taking of Bevacizumab or Ranibizumab or Aflibercept,

Aphakia in the studied eye,

Fibrosis or retrofoveolar retinal atrophy of the eye studied,

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed