Melanin and Dermal Uptake of Thirdhand Cigarette Smoke
ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity of California, San Francisco
About this trial
This is a pilot study of the effects of dermal melanin on dermal uptake and retention of nicotine. The initial hypothesis is that higher levels of dermal melanin will correlate with lower uptake and longer retention of nicotine in the skin and body.
Eligibility criteria
Qualifiers
Adult nonsmoker
Aged 18-50
Skin reflectance scores below 150 or above 249 using the Mexameter 18 instrument
Healthy on the basis of medical history
Disqualifiers
Dermal skin reflectance score between 150 and 249, as measured by the Mexameter 18 instrument.
Positive SARS-CoV-2 antibody test
Age 18 < or > 50
Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma.
Trial design
Treatments tested in this trial
- Wear clothing that has been exposed to cigarette smoke for 3 hours.
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov