Memory for Music: Individual Intensive Musical Training in Alzheimer's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorNORCE Norwegian Research Centre AS

About this trial

This project, called Memory for Music, focuses on the increasing number of people worldwide living with dementia, especially Alzheimer's disease (AD). AD typically starts with memory problems and eventually affects daily activities. Active music interventions, especially singing, have shown positive effects on mood, behavior, and quality of life for people with dementia, but their impact on cognition is not well understood. The project aims to address this gap by studying the effects of learning new songs on cognitive, behavioral, and brain functioning.

The study will involve home-dwelling adults aged 65 or older with AD from Argentina, Austria, and Norway. Participants will undergo 5 months of intensive musical training (twice a week) and 5 months of minimal training (once a month) in a random order, with a 2-month break in between. The interventions include learning new songs with a personal music teacher. General cognition will be measured using the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-cog), and memory for music will be assessed through various methods, including behavioral tasks and brain responses (EEG). Mood will also be evaluated in each session.

The goal is to include 113 participants to ensure reliable detection of meaningful effects. The study will explore how mood and memory for music contribute to changes in cognitive abilities, and whether these effects vary based on factors such as sex, age, AD stage, or previous musical training and general education. The project emphasizes collaboration between researchers, service providers, and users to ensure the study's relevance and applicability.

Eligibility criteria

Qualifiers

Diagnosis of Alzheimer's disease

Home-dwelling

Non-musician

Disqualifiers

Non-Alzheimer dementia

Living in care home

History as a professional musician

Trial design

Treatments tested in this trial

  • Music training - intensive
  • Music training - minimal
  • Treatment as Usual (TAU)

Treatment groups

113 Participants
are divided into 2 treatment groups

Sponsors and collaborators

NORCE Norwegian Research Centre AS

Lead sponsor

Universidad de Ciencias Empresariales y Sociales, Buenos Aires, Argentina

Collaborator

University of Vienna

Collaborator

University of Bergen

Collaborator

Universidad Nacional de Entre Rios

Collaborator

Kinn Municipality, Norway

Collaborator

Oslo Municipality

Collaborator

Norwegian Association for Music Therapy

Collaborator

Oslo Dementia Association

Collaborator